Craig Jolley
Graduate Student
Ph.D. (ASU Physics)
Home Department Physics
ASU Affiliations Physics
Areas of Study Protein structure, photosynthesis
Link Personal Homepage


Background In August 2008, I moved to Trevor Douglas's lab at Montana State University. You can find information about my current research activities here. My research efforts at ASU included:
  • Development of methods for the flexible fitting of atomic structures of macromolecules into lower-resolution electron density maps. We have used the bacterial chaperonin GroEL as a test system, and are beginning work on ferredoxin bound to cyanobacterial photosystem I.
  • Time-resolved optical spectroscopy on photosystem I supercomplexes from the green alga Chlamydomonas reinhardtii. Under limited light conditions, Chlamydomonas produces a variety of large membrane-intrinsic photosynthetic protein-pigment complexes. Optical methods allow us to study the basic energy transfer processes in these protein complexes on a femtosecond-picosecond timescale.
  • Molecular dynamics studies of detergent nanostructures. Detergents are commonly used to solubilize membrane proteins and are essential to any biochemical or biophysical study of these important proteins. When solvated by water, these detergents will form nanostructures such as bilayers or micelles -- we are interested in better understanding the structure of these detergent aggregates.

Stromal view of the PSI-LHCI supercomplex.

Fitting of GroEL into a cryo-EM electron density map

Transient absorption profile of Chlamydomonas photosystem I.
Craig-small.jpg
Craig Jolley
P.O. Box 871504
Tempe, AZ

fax: (480) 965-4669
email: craig.jolley
@asu.edu
[Publication] Jolley CC, Wells SA, Hespenheide BM, Thorpe MF, Fromme P (2006). Docking of Photosystem I subunit C using a constrained geometric simulation. JACS 128 (27), 8803-8812
[Publication] Subramanyam R, Jolley C, Brune DC, Fromme P, Webber AN (2006). Characterization of a novel Photosystem I-LHCI supercomplex isolated from Chlamydomonas reinhardtii under anaerobic (State II) conditions. FEBS Letters 580 (1), 233-238.
[Publication] Sener MK, Jolley C, Ben-Shem A, Fromme P, Nelson N, Croce R, Schulten K (2005). Comparison of the light-harvesting networks of plant and cyanobacterial photosystem I. Biophys. J. 89 (3), 1630-42.
[Publication] Jolley CC, Ben-Shem A, Nelson N, Fromme P (2005). Structure of plant photosystem I revealed by theoretical modeling. J. Biol. Chem. 280 (39), 33627-36.