Advisor
Alexander Fuhrmann
| Home Department | Physics |
Background Understanding the interactions of single biomolecules is crucial for the development of new kinds of drugs fighting various diseases like Alzheimer’s and diseases of the cardiovascular system. Studying these molecular recognitions by methods provided by the field of biological physics on the single molecule level allows very accurate determination of properties that would be lost in an ensemble measurement (e.g. intermediate states of binding processes). In my current research I focus on experiments of single molecule force spectroscopy (SMFS) of receptor-ligand pairs. My goal is to provide a better understanding of the physics involved and improve the data analysis methods. Furthermore, my studies include force spectroscopy experiments of cells and the challenging data analysis involved. My work also involves the combination of single molecule force spectroscopy and fluorescence microscopy. 2002 – 2006: Diploma Program - Bielefeld University 2006 – 2007: PhD Program – Bielefeld University 2008 – current: PhD Program – Arizona State University |
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[Publication]
A. Fuhrmann, J. C. Schoening, D. Anselmetti, D. Staiger and R. Ros; Quantitative analysis of single molecule RNA-protein interaction, Biophysical Journal, Volume 96, 5030-5039 (2009).
[Publication]
A. Fuhrmann, S. Getfert, D. Anselmetti, P. Reimann, and R. Ros;
Refined procedure of evaluating experimental single-molecule force spectroscopy data (Phys. Rev. E 77, 031912 (2008))