Kirill Speranskiy
Senior Technology Support Analyst
PhD, Carnegie Mellon University, Chemistry, 2007
| Home Department |
Physics |
| Areas of Study |
Protein-ligand binding, modeling of gated ion channels |
Background
To understand the receptor activation process one first needs to build a model of molecular basis. We studied mechanisms of receptor-ligand interactions, receptor activation and ion permeation in ion channels. |
[Publication]
Speranskiy K, Kurnikova M (2009)
Modeling of peptides connecting the ligand-binding and transmembrane domains in the GluR2 glutamate receptor.
Proteins: struc. func. and bioinf. 76 (2): 271-280
[Publication]
Speranskiy K, Cascio M, Kurnikova M (2007)
Homology Modeling and molecular dynamics simulations of the glycine receptor ligand binding domain.
Proteins: struc. func. and bioinf. 67 (4): 950-960
[Publication]
Speranskiy K, Kurnikova M (2005) On the binding determinants of the glutamate agonist with the glutamate receptor ligand binding domain.
Biochemistry 44 (34): 11508-11517
[Publication]
Speranskiy K, Kurnikova M (2004)
Accurate theoretical prediction of vibrational frequencies in an inhomogeneous dynamic environment: A case study of a glutamate molecule in water solution and in a protein-bound form.
J. chem. phys. 121 (3): 1516-1524