Kirill Speranskiy
Senior Technology Support Analyst
PhD, Carnegie Mellon University, Chemistry, 2007
Home Department Physics
Areas of Study Protein-ligand binding, modeling of gated ion channels


Background To understand the receptor activation process one first needs to build a model of molecular basis. We studied mechanisms of receptor-ligand interactions, receptor activation and ion permeation in ion channels.

Crystal structure of Glutamate ion channel ligand binding domain

Collagenase conformational change. Protein Pathways webportal: http://pathways.asu.edu
kirill_pic.JPG
Kirill Speranskiy
Center for Biological Physics
Arizona State University
PO Box 871504
Tempe, AZ 85287

phone: (480) 727-6416
fax: (480) 965-4669
email: kirill@asu.edu
[Publication] Speranskiy K, Kurnikova M (2009) Modeling of peptides connecting the ligand-binding and transmembrane domains in the GluR2 glutamate receptor. Proteins: struc. func. and bioinf. 76 (2): 271-280
[Publication] Speranskiy K, Cascio M, Kurnikova M (2007) Homology Modeling and molecular dynamics simulations of the glycine receptor ligand binding domain. Proteins: struc. func. and bioinf. 67 (4): 950-960
[Publication] Speranskiy K, Kurnikova M (2005) On the binding determinants of the glutamate agonist with the glutamate receptor ligand binding domain. Biochemistry 44 (34): 11508-11517
[Publication] Speranskiy K, Kurnikova M (2004) Accurate theoretical prediction of vibrational frequencies in an inhomogeneous dynamic environment: A case study of a glutamate molecule in water solution and in a protein-bound form. J. chem. phys. 121 (3): 1516-1524